LPLDL® in finished products –
CholBiome® Series

CholBiome®- Supporting Cardiovascular Health with LPLDL®

CholBiome offers a range of scientifically supported supplements that feature Lactobacillus plantarum LPLDL, the patented, naturally occurring probiotic strain supported by clinical studies. LPLDL offers a safe, effective and natural solution for cardiovascular health. Chosen from 4,000 candidates for its outstanding bile salt hydrolase activity and impact on cardiovascular biomarkers, LPLDL also has IP (intellectual property) rights secured by 29 patents and 2 trademarks.

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Why choose CholBiome?

  • Utilises specialised active ingredients for a multi-targeted approach
  • Each product is formulated to tackle key areas of cardiovascular health, including:
  • Cholesterol Management
  • Hypertension (high blood pressure)
  • Vascular Health (calcification)
  • Gastric acid protection technology is used for all products to ensure the active ingredients survive the journey through the stomach to deliver optimal performance
  • Documented and proven 2-year shelf-life stability studies at 25°C and 60%RH
  • Each product contains a minimum 4 billion CFU of LPLDL on expiry

The CholBiome Range

CHOLBIOME

For Cholesterol Maintenance

Contains LPLDL as the active ingredient to support healthy cholesterol and blood pressure management. These benefits are also present in each product within the range.

  • Supported by a double-blind placebo-controlled study to:
  • Reduce Total Cholesterol by 36.7%
  • Reduce LDL-cholesterol by 13.9%
  • Reduce blood pressure by 5.1%
  • Boost HDL Cholesterol by 4.5%
  • Reduces Apo-B which is a key factor in artery plaque formation
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CholBiomeX3

For Cholesterol Reduction

Contains 3 ingredients in a unique triple layer tablet; LPLDL, red yeast rice rich in monacolin K and Niacin (vitamin B3) to reduce cholesterol.

 

Supporting EFSA health claim:

“Monacolin K from red yeast rice contributes to the maintenance of normal blood cholesterol levels.”

  • Combines 2 synergistic ingredients with mechanics to reduce blood cholesterol as well as inhibit cholesterol production
  • More than 95% of consumers said CholBiomeX3 is effective (2019 Consumer study)
  • A unique 3-layer tablet ensures a superior probiotic cell count survival in combination with previously non-compatible actives
More Product Info

CholBiomeCH

For Dual Action Cholesterol Reduction

Contains 2 active ingredients in a bi-layer tablet LPLDL® and plant sterols/stanols to deliver a unique dual action cholesterol reducing formula. CholBiome®CH combines two synergistic ingredients to support the reduction both internal and dietary cholesterol levels.

Supporting EFSA health claim:

“Plant sterols/stanols contribute to the maintenance of normal blood cholesterol levels.”

  • Combines 2 dual action ingredients to support the reduction in both internal and dietary cholesterol
  • A clinical trial from the University of Roehampton which documented statistically significant findings in cholesterol reduction​
  • A unique bi-layer tablet ensures a superior probiotic cell count survival in combination with previously non-compatible actives
More Product info

CholBiomeBP

For Blood Pressure Reduction

Contains 4 ingredients in a unique triple layer tablet; LPLDL, Thiamine (vitamin B1), L-arginine and CoEnzyme Q10 to reduce high blood pressure.

Supporting EFSA health claim:

“Thiamine contributes to the normal function of the heart.”

  • 4 synergistic ingredients help support normal blood circulation and pressure
  • A clinical trial from the University of Pavia which documented statistically significant findings on blood pressure reduction
  • The only probiotic strain globally, showing simultaneous reductions in both LDL cholesterol as well as blood pressure
More Product Info
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CholBiomeVH

For Calcification Reduction (Vascular health)

Contains 3 ingredients within a HPMC capsule; LPLDL, Thiamine (Vitamin B1) and K2VITAL® (Vitamin K2)

Supporting EFSA health claim:

“Thiamine contributes to the normal function of the heart” and “Vitamin K contributes to normal blood coagulation”.

  • 3 synergistic ingredients specifically chosen for their capacity to support the reduction in vascular calcification and plaque formation in arteries
  • Harnesses the synergistic capabilities of 2 patented and scientifically supported ingredients, LPLDL from ProBiotix Health and K2VITAL from Kappa Biosciences
More Product Info

The CholBiome series utilises different active ingredients for a multi-targeted approach. Each product is formulated to tackle various areas of cardiovascular health, including: cholesterol management, hypertension and vascular health.

Whether in tablet or capsule format, each product comes with gastric acid protection technology. Considering 80-90% of bacteria is killed in the stomach, this is required to ensure the probiotic survives the journey to the intestine, and delivers optimal performance.

Health claim references

1) EFSA Journal 2011;9(7):2304
2) EFSA Journal 2010;8(10):1757
3) EFSA Journal 2009;7(9): 1228

Award recognition

LPLDL is an industry recognised ingredient, and has been a runner up in multiple leading
industry awards within probiotic categories.  

Best Functional
Ingredient of the Year
Probiotic Product
of the Year
Miscellaneous
University of Reading Final Year graduate won the IFST award for Young Scientist Competition 2019 at IPC utilising LP LDL
Probiotic Product
of the Year
Best Nutraceutical
Product of the Year
Probiotic Product
of the Year
Best Gut Health & Heart
Health Product

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For more information on Lactobacillus plantarum LPLDL®, please contact us

ProBiotix Health

Cavalier Suite, The Barracks, Wakefield Road, Pontefract, England, WF8 4HH

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Contact us

lpldl@probiotixhealth.com